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The United States embargo against Cuba is a commercial, economic, and financial embargo partially imposed on Cuba in October 1960. It was enacted after Cuba nationalized the properties of United States citizens and corporations and it was strengthened to a near-total embargo since February 7, 1962.

Titled the Cuban Democracy Act, the embargo was codified into law in 1992 with the stated purpose of maintaining sanctions on Cuba so long as the Cuban government continues to refuse to move toward "democratization and greater respect for human rights".
In 1996, Congress passed the Helms-Burton Act, which further restricted United States citizens from doing business in or with Cuba, and mandated restrictions on giving public or private assistance to any successor government in Havana unless and until certain claims against the Cuban government are met. In 1999, U.S. President Bill Clinton expanded the trade embargo even further by ending the practice of foreign subsidiaries of U.S. companies trading with Cuba. In 2000, Clinton authorized the sale of certain "humanitarian" US products to Cuba.

It has been argued that pro-embargo Cuban-American exiles, whose votes are crucial in Florida, have swayed many politicians to also adopt similar views. The Cuban-American views have been opposed by business leaders who argue that trading freely would be good for Cuba and the United States. At present, the embargo, which limits American businesses from conducting business with Cuban interests, is still in effect and is the most enduring trade embargo in modern history. Despite the existence of the embargo, the United States is the fifth largest exporter to Cuba (6.6% of Cuba's imports are from the US). However, Cuba must pay cash for all imports, as credit is not allowed.
On September 2, 2010, President Barack Obama extended the embargo through September 14, 2011, determining that the embargo "is in the national interest of the United States."